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Germs, Genes, & Civilization

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Friday, December 27, 2013

Germs, Genes, & Civilization: How Epidemics Shaped Who We Are Today (FT Press Science) Hardcover – May 22, 2010

Author: Visit Amazon's David P. Clark Page | Language: English | ISBN: 0137019963 | Format: PDF, EPUB

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Germs, Genes, & Civilization: How Epidemics Shaped Who We Are Today – May 22, 2010
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From Publishers Weekly

Clark (Molecular Biology Made Simple and Fun) argues that microscopic bacteria, viruses, and fungi have played an enormous and largely unacknowledged role in human history. Beginning with Attila's attack of Rome, which was likely stopped by dysentery, and continuing through modern diseases such as AIDS and the Ebola virus, Clark investigates a large number of illnesses and uncovers the ways in which they have impacted historical events. The same genes that provide humanity with protection against some endemic diseases, Clark argues, may also cause sickle cell anemia and cystic fibrosis. With wit and humor, the author turns death, an ever-heavy topic, into an engrossing exploration of the course of mankind. Though Clark's lack of references will make it difficult for readers to gain additional information, there's much of interest in this chronicle of microbes through the ages.
Copyright © Reed Business Information, a division of Reed Elsevier Inc. All rights reserved.

About the Author

David Clark was born June 1952 in Croydon, a London suburb. After winning a scholarship to Christ’s College, Cambridge, he received his Bachelor of Arts degree in 1973. In 1977, he earned his Ph.D. from Bristol University for work on antibiotic resistance. David then left England for postdoctoral research at Yale and then the University of Illinois. He joined the faculty of Southern Illinois University in 1981 and is now a professor in the Microbiology Department. In 1991, he visited Sheffield University, England, as a Royal Society Guest Research Fellow. The U.S. Department of Energy funded David’s research into the genetics and regulation of bacterial fermentation from 1982 till 2007. David has published more than 70 articles in scientific journals and graduated more than 20 masters and Ph.D. students. David is the author of Molecular Biology Made Simple and Fun, now in its third edition, as well as three more serious textbooks.


Direct download links available for Germs, Genes, & Civilization: How Epidemics Shaped Who We Are Today (FT Press Science) Hardcover – May 22, 2010
  • Series: FT Press Science
  • Hardcover: 304 pages
  • Publisher: FT Press; 1 edition (May 22, 2010)
  • Language: English
  • ISBN-10: 0137019963
  • ISBN-13: 978-0137019960
  • Product Dimensions: 1.4 x 5.9 x 9 inches
  • Shipping Weight: 1.3 pounds (View shipping rates and policies)
  • Amazon Best Sellers Rank: #1,161,251 in Books (See Top 100 in Books)
I loved "Guns, Germs, and Steel" and was looking forward to another exciting book on the impact of disease on history. Unfortunately, this is not it. There are some great stories in this book, but overall it reads like a series of undergraduate lectures delivered with minimal fact-checking to an uncritical audience. In a book intended for non-scientists, it's appropriate to omit citations within the text, but no sources are listed anywhere, even for whole chapters and the most controversial claims. As teachers, we plead with students not to take claims at face value, but to look at the evidence. Books are listed at the end for "further reading," but no research articles. There's not much 21st century updating- surely the lovely stories about Helicobacter and language co-evolution and the scary ones about XDR-TB belong here. Prof. Clark knows his microbiology, but is incurious about human genetics, anthropology, and HIV epidemiology, to name just three fields central to his speculations. We are told (p. 15) that the sickle cell mutation is found "only in Africans indigenous to regions harboring P. falciparum malaria". This is just not true. The same mutation is found at relatively high frequencies in Greek, Saudi Arabian, East Indian, and other populations exposed to falciparum malaria; it has evolved independently at least five times. He speculates that differences in sexual permissiveness account for Christian vs Muslim differences in HIV prevalence rates in subSaharan Africa. For several years it's been known that circumcision is highly protective and explains most of these differences. "in Africa...AIDS will thin out the promiscuous and malnourished, and favor the spread of religious puritanism, particularly Islamic sects..." (p. 253).

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