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Clinical Pharmacokinetics and Pharmacodynamics

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Pharmacology
Tuesday, December 17, 2013

Clinical Pharmacokinetics and Pharmacodynamics: Concepts and Applications Hardcover – January 28, 2010

Author: Visit Amazon's Malcolm Rowland Page | Language: English | ISBN: 0781750091 | Format: PDF, EPUB

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Clinical Pharmacokinetics and Pharmacodynamics: Concepts and Applications – January 28, 2010
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Review

-- "This textbook covers a tremendous range of topics important in pharmacokinetics and pharmacodynamics. No other textbook does this as effectively as the Rowland and Tozer text." -- "I believe this book is the best written text for bridging the gap between basic PK and clinical PK."

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  • Hardcover: 864 pages
  • Publisher: LWW; Fourth edition (January 28, 2010)
  • Language: English
  • ISBN-10: 0781750091
  • ISBN-13: 978-0781750097
  • Product Dimensions: 1.5 x 7.1 x 9.8 inches
  • Shipping Weight: 3.8 pounds (View shipping rates and policies)
  • Amazon Best Sellers Rank: #29,672 in Books (See Top 100 in Books)
    • #42 in Books > Textbooks > Medicine & Health Sciences > Medicine > Clinical > Internal Medicine
    • #42 in Books > Textbooks > Medicine & Health Sciences > Medicine > Basic Sciences > Pharmacology
    • #55 in Books > Textbooks > Medicine & Health Sciences > Allied Health Services > Pharmacy
"Clinical Pharmacokinetics: Concepts and Applications" (or better known as Rowland and Tozer) is a book filled with deep concepts and good explanations. It is the Bible of Pharmacokinetics. If there is a PK concept you want to look up, this book will be the first place you look for it. Before giving the review, let me introduce my background. I have a formal education in physical chemistry and analytical chemistry and am currently working in the field of pharma. I have currently read through half of this book. Although I have not completely finishing the book, I believe there is enough information to share.

The previous PK book I read was Concepts In Clinical Pharmacokinetics by Joseph T. Dipiro and it is a shorter and simpler book than Rowland and Tozer. While "Concepts In Clinical Pharmacokinetics" was a delight to read, it is on the simpler side and a lot of concepts are left unexplained. When I was reading it, there were often moment of "How did he get from this to that?" or "Where this comes from?", and I had to stop reading and tried to derive the equations. In contrast, Rowland and Tozer explain the principles of PK in great details and often from multiple angles, so that the readers can fully appreciate how the concepts are linked together, how PK theories apply and how PK impacts pharmacology research and the drug discovery. The exercises are challenging, but not impossible. Well, a few of them are nearly impossible, but most of them can be worked out (even for someone of my background).

I would love to give it a 4.5 stars, but that is not an option.

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